Back Pain Study

Information for Patients

We are currently analyzing data from our back pain studies and preparing our findings for publication. We are not currently enrolling new patients in any of our back pain studies.

What is Chronic Low Back Pain?

Chronic low back pain is defined as pain that lasts more than 3 months.  The pain is located in the low back and can worsen with bending, sitting, or even turning over in bed.  Sneezing or coughing can sometimes make the pain worse.  Occasionally, the pain can radiate to the buttocks or down a leg.

What Causes Low Back Pain?

There are many causes of low back pain and it can be due to strain of the muscles or ligaments of the back or injury to the bones or discs that comprise the spine. Often, we are unable to determine an exact event or injury responsible for chronic low back pain. 

What Treatments Are Available for Chronic Low Back Pain?

Chronic back pain is a very common medical problem.  Unfortunately, there are not many effective treatments for chronic low back pain (e.g. lasting more than 3 months).  Sometimes the pain will improve on its own.  Drug therapies such as non-steroidal anti-inflammatory drugs (NSAIDs) are common. Another common treatment for moderate to severe chronic back pain is the use of opioid pain medications. However, opioid physical dependency is a potential side effect of extended opioid use. Our study aims to reduce these side effects with a complementary medication called Ondansetron.

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